---
slug: "protein-design-skills"
source_type: "readme"
source_url: "https://cdn.jsdelivr.net/gh/adaptyvbio/protein-design-skills@main/README.md"
repo: "https://github.com/adaptyvbio/protein-design-skills"
source_file: "README.md"
branch: "main"
---
<p align="center">
  <img src="assets/hero_animation.svg" width="560" alt="Protein Design Skills">
</p>

<p align="center">
  <strong>24 Claude Code skills for computational protein design</strong>
</p>

<p align="center">
  <a href="docs/getting-started.md">Getting started</a> •
  <a href="docs/skills.md">Skills</a> •
  <a href="docs/standard-pipeline.md">Pipeline</a>
</p>

---

## Install

```
/plugin marketplace add adaptyvbio/protein-design-skills
/plugin install adaptyv@protein-design-skills
```

---

## Setup (first time)

<p align="center">
  <img src="assets/setup_steps.svg" width="600" alt="Setup steps">
</p>

→ [Getting started](https://github.com/adaptyvbio/protein-design-skills/blob/HEAD/docs/getting-started.md)

---

## Skills

<p align="center">
  <img src="assets/skill_categories.svg" width="550" alt="Skill categories">
</p>

→ [View all 24 skills](https://github.com/adaptyvbio/protein-design-skills/blob/HEAD/docs/skills.md)

---

## Pipeline

<p align="center">
  <img src="assets/pipeline_flow.svg" width="550" alt="Pipeline flow">
</p>

→ [Standard pipeline](https://github.com/adaptyvbio/protein-design-skills/blob/HEAD/docs/standard-pipeline.md)

---

## Quick start

> "Design a binder for PDB 1ALU"

Claude will pick the right skills for the target (for example BoltzGen → Chai → QC,
or RFdiffusion → ProteinMPNN → Chai → QC).

---

## Links

- [Getting started](https://github.com/adaptyvbio/protein-design-skills/blob/HEAD/docs/getting-started.md)
- [Skills](https://github.com/adaptyvbio/protein-design-skills/blob/HEAD/docs/skills.md)
- [Standard pipeline](https://github.com/adaptyvbio/protein-design-skills/blob/HEAD/docs/standard-pipeline.md)
- [Compute setup](https://github.com/adaptyvbio/protein-design-skills/blob/HEAD/docs/compute-setup.md)
- [Contributing](https://github.com/adaptyvbio/protein-design-skills/blob/HEAD/CONTRIBUTING.md)

---

## Contributing

### Creating a new skill

The easiest way to create a new skill is with Claude Code:

```
/skill skill-creator
```

This uses [Anthropic's skill-creator](https://github.com/anthropics/skills/tree/main/skills/skill-creator) to guide you through the process.

See [CONTRIBUTING.md](https://github.com/adaptyvbio/protein-design-skills/blob/HEAD/CONTRIBUTING.md) for detailed guidelines.

---

## License

MIT

## References

- [biomodals](https://github.com/hgbrian/biomodals) - Modal execution wrappers
- [Anthropic Skills](https://github.com/anthropics/skills) - Skills specification